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Jafari A, Peeri M, Azarbayejani M, Homai H. Effect of Resistance Training on Appetite Regulation and Level of Related Peptidesin Sedentary Healthy Men. mljgoums 2017; 11 (4) :24-29
URL: http://mlj.goums.ac.ir/article-1-1025-en.html
URL: http://mlj.goums.ac.ir/article-1-1025-en.html
1- Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Islamic Azad University, Central Tehran Branch, Tehran, Iran
Abstract: (10690 Views)
ABSTRACT
Background and Objectives: Resistance training is a key component of exercise recommendations for weight control, yet very little is known about the effects of resistance training on appetite and related peptides. Hence, the aim of the present study was to investigate the effect of 8 weeks of resistance training on appetite and circulating acyl ghrelin, neuropeptide Y (NPY), and orexin in sedentary men.
Methods: This study included 20 sedentary men (mean age: 21.6±3.5 year, body mass index: 23.1±2.7 kg/m2) who were equally divided into a control group and a resistance training group. Participants in the training group performed the whole body exercises three sessions per week with 3-4 sets of 8-10 repetitions at 60-85% one-repetition maximum. Participants in the control group performed no resistance training. Fasting blood samples were taken before starting the study and 72 hours after the last session of resistance training for evaluation of serum acyl ghrelin, NPY, and orexin levels. In addition, perceived appetite was assessed by visual analogue scale while fasting.
Results: Statistical analysis showed that fasting acyl ghrelin and NPY were not changed by resistance training, but serum orexin level elevated by 40% in response to training (P=0.01). Appetite was not significantly different between the two groups at baseline (P=0.9). However, appetite significantly increased after resistance training (P=0.001).
Conclusion: Results of the present study show that the 8-week resistance training increases perceived appetite by orexin promotion in previously sedentary men.
Keywords: Appetite, Ghrelin, NPY, Orexins, Resistance Training.
Background and Objectives: Resistance training is a key component of exercise recommendations for weight control, yet very little is known about the effects of resistance training on appetite and related peptides. Hence, the aim of the present study was to investigate the effect of 8 weeks of resistance training on appetite and circulating acyl ghrelin, neuropeptide Y (NPY), and orexin in sedentary men.
Methods: This study included 20 sedentary men (mean age: 21.6±3.5 year, body mass index: 23.1±2.7 kg/m2) who were equally divided into a control group and a resistance training group. Participants in the training group performed the whole body exercises three sessions per week with 3-4 sets of 8-10 repetitions at 60-85% one-repetition maximum. Participants in the control group performed no resistance training. Fasting blood samples were taken before starting the study and 72 hours after the last session of resistance training for evaluation of serum acyl ghrelin, NPY, and orexin levels. In addition, perceived appetite was assessed by visual analogue scale while fasting.
Results: Statistical analysis showed that fasting acyl ghrelin and NPY were not changed by resistance training, but serum orexin level elevated by 40% in response to training (P=0.01). Appetite was not significantly different between the two groups at baseline (P=0.9). However, appetite significantly increased after resistance training (P=0.001).
Conclusion: Results of the present study show that the 8-week resistance training increases perceived appetite by orexin promotion in previously sedentary men.
Keywords: Appetite, Ghrelin, NPY, Orexins, Resistance Training.
Research Article: Original Paper |
Received: 2017/12/16 | Accepted: 2017/12/16 | Published: 2017/12/16 | ePublished: 2017/12/16
Received: 2017/12/16 | Accepted: 2017/12/16 | Published: 2017/12/16 | ePublished: 2017/12/16
References
1. Druce M, Bloom S. The regulation of appetite. Archives of disease in childhood. 2006;91(2):183-7.doi: 10.1136/adc.2005.073759. [DOI:10.1136/adc.2005.073759]
2. Saghebjoo M, Hedayati M, Fahimi Y, Ilbeigi S. Plasma acylated ghrelin response to one session circuit resistance exercise in fasted and high carbohydrate meal in healthy young men. International journal of endocrinology and metabolism. 2013;11(4): e8568. doi: 10.5812/ijem.8568. [DOI:10.5812/ijem.8568]
3. Perry B, Wang Y. Appetite regulation and weight control: the role of gut hormones. Nutrition & diabetes. 2012;2(1):e26. [DOI:10.1038/nutd.2011.21]
4. Rahmani-Nia F, Mirzaei B, Rahimi R. Effects of resistance exercise volume on appetite regulation and lipid profile in overweight young men. Science & Sports. 2015;30(5):290-7. [DOI:10.1016/j.scispo.2015.04.008]
5. Murphy KG, Bloom SR. Gut hormones and the regulation of energy homeostasis. Nature. 2006;444(7121):854-9. [DOI:10.1038/nature05484]
6. Druce M, Wren A, Park A, Milton J, Patterson M, Frost G, et al. Ghrelin increases food intake in obese as well as lean subjects. International journal of obesity. 2005;29(9):1130-6. [DOI:10.1038/sj.ijo.0803001]
7. Druce M, Neary N, Small C, Milton J, Monteiro M, Patterson M, et al. Subcutaneous administration of ghrelin stimulates energy intake in healthy lean human volunteers. International journal of obesity. 2006;30(2):293-6. [DOI:10.1038/sj.ijo.0803158]
8. Kokot F, Ficek R. Effects of neuropeptide Y on appetite. Mineral and electrolyte metabolism. 2000;25(4-6):303-5. [DOI:10.1159/000057464]
9. Martynska L, Wolinska-Witort E, Chmielowska M, Bik W, Baranowska B. The physiological role of orexins. Neuro Endocrinol Lett. 2005;26(4):289-92.
10. Tomasik PJ, Spodaryk M, Sztefko K. Plasma concentrations of orexins in children. Annals of nutrition and metabolism. 2004;48(4):215-20. [DOI:10.1159/000080453]
11. Ghanbari-Niaki A, Nabatchian S, Hedayati M. Plasma agouti-related protein (AGRP), growth hormone, insulin responses to a single circuit-resistance exercise in male college students. Peptides. 2007;28(5):1035-9. [DOI:10.1016/j.peptides.2007.02.004]
12. Guelfi KJ, Donges CE, Duffield R. Beneficial effects of 12 weeks of aerobic compared with resistance exercise training on perceived appetite in previously sedentary overweight and obese men. Metabolism. 2013;62(2):235-43. [DOI:10.1016/j.metabol.2012.08.002]
13. Stubbs RJ, Hughes DA, Johnstone AM, Rowley E, Reid C, Elia M, et al. The use of visual analogue scales to assess motivation to eat in human subjects: a review of their reliability and validity with an evaluation of new hand-held computerized systems for temporal tracking of appetite ratings. British Journal of Nutrition. 2000;84(04):405-15. [DOI:10.1017/S0007114500001719]
14. Kraemer WJ, Ratamess NA. Hormonal responses and adaptations to resistance exercise and training. Sports Medicine. 2005;35(4):339-61. [DOI:10.2165/00007256-200535040-00004]
15. Neary NM, Goldstone AP, Bloom SR. Appetite regulation: from the gut to the hypothalamus. Clinical endocrinology. 2004;60(2):153-60. [DOI:10.1046/j.1365-2265.2003.01839.x]
16. Hazell TJ, Islam H, Townsend LK, Schmale MS, Copeland JL. Effects of exercise intensity on plasma concentrations of appetite-regulating hormones: Potential mechanisms. Appetite. 2016;98:80-8. [DOI:10.1016/j.appet.2015.12.016]
17. Tiryaki-Sonmez G, Ozen S, Bugdayci G, Karli U, Ozen G, Cogalgil S, et al. Effect of exercise on appetite-regulating hormones in overweight women. Biology of sport. 2013;30(2):75-80. [DOI:10.5604/20831862.1044220]
18. Balaguera-Cortes L, Wallman KE, Fairchild TJ, Guelfi KJ. Energy intake and appetite-related hormones following acute aerobic and resistance exercise. Applied Physiology, Nutrition, and Metabolism. 2011;36(6):958-66. [DOI:10.1139/h11-121]
19. Khalilzadeh M, Azali Alamdari K, Choobineh S, Ebadi Shirmard B, Ghahramani M. Effects of Aerobic Training with Low and Intermediate Intensity on Appetite, Body Weight, Exercise Energy Expenditure and Plasma Ghrelin level in Relatively Thin and Obese Sedentary Women. Iranian Journal of Nutrition Sciences & Food Technology. 2011;6(1):1-10.
20. Foster-Schubert KE, McTiernan A, Frayo RS, Schwartz RS, Rajan KB, Yasui Y, et al. Human plasma ghrelin levels increase during a one-year exercise program. The Journal of Clinical Endocrinology & Metabolism. 2005;90(2):820-5. [DOI:10.1210/jc.2004-2081]
21. Leidy H, Gardner J, Frye B, Snook M, Schuchert M, Richard E, et al. Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young women. The journal of clinical endocrinology & metabolism. 2004;89(6):2659-64. [DOI:10.1210/jc.2003-031471]
22. Martins C, Kulseng B, King N, Holst JJ, Blundell J. The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat. The Journal of Clinical Endocrinology & Metabolism. 2010;95(4):1609-16.doi: 10.1210/jc.2009-2082. [DOI:10.1210/jc.2009-2082]
23. Toshinai K, Date Y, Murakami N, Shimada M, Mondal MS, Shimbara T, et al. Ghrelin-induced food intake is mediated via the orexin pathway. Endocrinology. 2003;144(4):1506-12. [DOI:10.1210/en.2002-220788]
24. Shimizu S, Nakamachi T, Konno N, Matsuda K. Orexin A enhances food intake in bullfrog larvae. Peptides. 2014;59:79-82.doi: 10.1016/j.peptides.2014.07.013. [DOI:10.1016/j.peptides.2014.07.013]
25. Nakamachi T, Shibata H, Sakashita A, Iinuma N, Wada K, Konno N, et al. Orexin A enhances locomotor activity and induces anxiogenic-like action in the goldfish, Carassius auratus. Hormones and behavior. 2014;66(2):317-23.doi: 10.1016/j.yhbeh.2014.06.004. [DOI:10.1016/j.yhbeh.2014.06.004]
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