1- Assistant professor of Gynaecologist, Golestan University of Medical Sciences , tabande_a@yahoo.com
2- General Practitioner,Golestan University of Medical Sciences
3- Assistant Professor, Golestan University of Medical Sciences
Abstract: (18463 Views)
Abstract
Background and Objective: Pre-eclampsia is the most common cause of maternal and neonatal mortality. Recent studies show that there may be a relationship between chorionic gonadotropine (HCG) and pre-eclampsia. Thus we aimed at assessing the serum level of βhCG after 28th week of pregnancy in mild pre-eclamptic and healthy pregnant women.
Material and Methods: In this case-control study, we measured the level of βhCG in 26 pre-eclamptic and 26 normal pregnant women. The difference between groups was analyzed by Mann-Whitney test (P≤ 0.05).
Results: The mean of βhCG in the case (73192 ± 42956 IU/L) and control group (34038 ± 21272 IU/L) is different significantly (P= 0.001). Considering mother’s age, gestational age and parity, there is a significant difference between the two groups (P=0.001).
Conclusion: The results of our study show that the higher level of βhCG, the greater the risk of pre-eclampsia.
Key words: Pre eclampsia, βhCG, Parity
Research Article:
Brief Report |
Received: 2013/05/7 | Accepted: 2013/05/26 | Published: 2013/05/26 | ePublished: 2013/05/26