Showing 17 results for Arab
H Bazzazi, M.a. Ramezani, M Bazoori, A Mohamadi Bondarkheili, M Arabahmadi, A Ghaemi,
Volume 1, Issue 1 (Spring - Summer 2007 [PERSIAN] 2007)
Abstract
Abstract
Background and objectives:
most common causes of morbidity and mortality in industrial and
developing countries. Recent studies have suggested that
A coronary heart disease is one of the
Helicobacter pylori
heart disease therefore, this study was carried out in Gorgan, Iran, to
show the relationship between coronary disease and Helicobacter
pylori infection.
caused infection may be associated with chronic
Materials and Methods:
carried out on 109 patients suffering from acute coronary syndrome
and 85 healthy individuals, ELISA was used to determine Anti
Helicobacter pylori Anti bodies (IgA, IgG ).
In this cross sectional case-control study
Results:
while in control group were %32.9 and %62.4. There was significant
difference between IgA of two groups (p<0.007). Simultaneous
presence of both IgG and IgA in patients affected by Coronary disease
was meaningful (p<0.003).
IgA and IgG antibodies of case group were %51.4 and %53.2
Conclusion
be related to coronary disease, we suggest their investigation in
suspected individuals.
: Since Simultaneous presence of both IgG and IgA may
Key word
Antibody
: Acute Coronary syndrome, Helicobacter Pylori,
M Hedayat Mofidi, A Moradi, M Saeedi, N Behnampoor, J Arab Yaramohammadi,
Volume 2, Issue 1 (Spring - Summer 2008[PERSIAN] 2008)
Abstract
Abstract Backgrounds and objectives: Herpes simplex virus type 1 (HSV- 1) infections are mostly shown as a Herpes disease, but It causes conjunctivitis, genital herpes, encephalitis and newborn herpes. This study was conducted to determine the sero-epidemiologic prevalence of herpes simplex virus type 1 in cases referred to clinical laboratories of Gorgan, Iran. Material and methods: In this cross sectional study, we did random blood sampling on 406 cases referred to the Gorgan city's clinical laboratories. These samples were analyzed for HSV-1 Immunoglobulin G and M antibodies using type- specific enzymelinked Immunoassays (ELISA). Results: Of 406 participants, the HSV-1 seroprevalence is 49% (44.3% and 4.7% for IgG and IgM respectively). There is not significant relationship between seropositive HSV-1 and gender, ethnicity, age and marital status. Conclusion: Sero-epidemiological of HSV-1 in Gorgan is the same of the other places in Iran, but it is higher than European and lower than African countries. It seems that the people’s culture is very important. Therefore it needs to be investigated more. Keywords: HSV-1, Antibody, Gorgan.
N Ziaei, N Amir Mozafari, H Kouhsari, A Moradi, A Tabarai, T Dadgar, S Livani, M Arab Ahmadi,
Volume 2, Issue 2 (Autumn – Winter 2009[PERSIAN] 2008)
Abstract
Abstract Background and Objectives: Diarrhea is one of the most common diseases in the world. Campylobacter jejuni is one of the prevalent agents of bacterial diarrhea in most of developing countries. It is usually ignored in routine laboratory test in our country, because it has a difficult investigation method. This article aims to determine the prevalence of Campylobacter jejuni, in diarrhea samples in Gorgan City (East north of Iran) by PCR Method. Material and Methods: This descriptive study was performed on 455 diarrheal samples during one year (2005-06).255 out of them were cultured on Preston media (Himedia co.) on 42°c. DNA Extracted by phenol cholorophorm method was directly carried out on stool samples.16srDNA hipo and asp primers for detection of Campylobacter genus, C.jejuni and C.coli species were used, respectively. In addition, universal primer of 16srDNA was used for control of PCR method. Results: no sample was positive for Campylobacter in culture .only three samples were positive for Campylobacter genus and C.jejuni specific primer but none of them were positive for C.coli .99 samples were positive by universal primer of 16srDNA . Conclusion: The results indicate that C.jejuni isn't a prevalent agent in diarrhea in our region. Key words: Campylobacter jejuni -Gorgan- Diarrhea
S S Bani Aghil, S Abbasi, M Arab, M S Seyedein,
Volume 3, Issue 2 (Autumn – Winter 2010[PERSIAN] 2009)
Abstract
Abstract Background and objectives: Hepatitis C virus (HCV), Human immuno deficiency virus (HIV) and Hepatitis B Virus (HBV) are the three main agents of Communicable disorders transmitted by blood transfusion. The survey of these virus-caused infections in Blood donors can display epidemiology of infections in province and be useful for evaluating donors’ health. The aim of this study was serologic Study of infections caused by HBV, HCV and HIV in Blood donors of Golestan province, Iran. Material and Methods: This retrospective study was carried out on all files of blood donors, referred to Golestan Blood transfusion Services, with positive Lab results. We assess the prevalence of HBV, HCV and HIV, and demographic data of blood donors and analyzed the data by chi-square, using SPSS soft ware. Results: During 2006-2008, 128198 people have donated in Golestan province. The prevalence of HBV during 2006-2008 is respectively 1.25%, 0.95% and 0.11% HCV is 14%, 13% and of HIV is 0.0015 %( just 2 cases in 2007). The prevalence of HBV, HIV and HCV is higher in male, married and donors with high school diploma. Also the prevalence of HIV, HCV and HBV is lower in regular donors rather the first time donors. Conclusion: It seems that the prevalence of HBV and HCV is decreased during three years. This decrease can be due to physician’s supervision for selecting healthy donor and availability of donors’ medical record. Key words: Golestan Province, HIV, HCV, HBV, demographic,prevalence
A Tabandeh, H Organji, M Aarabi,
Volume 7, Issue 1 (spring[PERSIAN] 2013)
Abstract
Abstract
Background and Objective: Pre-eclampsia is the most common cause of maternal and neonatal mortality. Recent studies show that there may be a relationship between chorionic gonadotropine (HCG) and pre-eclampsia. Thus we aimed at assessing the serum level of βhCG after 28th week of pregnancy in mild pre-eclamptic and healthy pregnant women.
Material and Methods: In this case-control study, we measured the level of βhCG in 26 pre-eclamptic and 26 normal pregnant women. The difference between groups was analyzed by Mann-Whitney test (P≤ 0.05).
Results: The mean of βhCG in the case (73192 ± 42956 IU/L) and control group (34038 ± 21272 IU/L) is different significantly (P= 0.001). Considering mother’s age, gestational age and parity, there is a significant difference between the two groups (P=0.001).
Conclusion: The results of our study show that the higher level of βhCG, the greater the risk of pre-eclampsia.
Key words: Pre eclampsia, βhCG, Parity
M Darabi, Sh Jahani Zadeh, M Chegeny,
Volume 8, Issue 2 (summer 2014[PERSIAN] 2014)
Abstract
Abstract
Background and Objective: Quality control of drinking water is important for maintaining health and safety of consumers, and the first step is to study the water quality variables. This study aimed to evaluate the chemical and physical indicators, water quality variables and qualitative classification of drinking water stations and water sources in Boroujerd.
Material and Methods: This descriptive-cross sectional study was conducted on 70 samples of drinking water and 10 samples from sources in 2011-2012. Nine Water quality variables were measured and coded using STATISTICA10 Software. Principal component analysis (PCA) was performed for qualitative classification of water samples and determination of water quality variables.
Results: Based on PCA, chemical variables such as fluoride, nitrate, total hardness and iron, and physical variables such as pH and TDS were paramount importance to water quality. According to T-test, the average concentration of fluoride and iron, and the turbidity in all samples were significantly less than the standard. But other variables were up to standard.
Conclusion: For the large water quality data, the use of PCA to identify the main qualitative variables and to classify physical and chemical variables
can be used as an effective way in water quality management.
Keywords: Physical and Chemical Indicators, Drinking Water and Sources, Boroujerd, Principal Component Analysis
Azadi F, Hedayat Mofidi, M , Ali Arab, A , Hedayat Mofidi, H , Khorasaninjad, R , Ghasemi-Kebria, F , Roshandel, Gh ,
Volume 9, Issue 3 (Jul,Aug2015[PERSIAN] 2015)
Abstract
Background and Objective: Helicobacterpylori(HP) is the most common bacterial infection in the world and it may be associated with chronic gastritis, pepticulcer disease, and gastricadenocarcinoma. The aim of this study was to determine the prevalence of HP in student of Golestan University of Medical Sciences (GOUMS).
Material and Methods: This cross-sectional study was conducted on students ofGOUMS in 2012. Anti-HP IaG and IgA were assessed byELISA method.
Results: The participants recruited were 287 in that 101 (35.2%) were male and the rest female. Of 287 , 239 (83.3%) were positive for HP. The proportion of men was 91.1% and women 79% (P =0.03). There was no significant relationship between HP infection and variables such as age, blood group , place of residence, nativity, and level of education.
Conclusion: The prevalence of H. pylori infection in the students of Golestan University of Medical Sciences is high.
Gholipoory, M, Rezai, Hr, Namroodi, S, Arabkhazaeli, F,
Volume 9, Issue 3 (Jul,Aug2015[PERSIAN] 2015)
Abstract
Abstract
Background and Objective: Given the Leishmaniasis is endemic in Turkmen Sahra, we aimed to study the contamination of rodents with this disease.
Material and Methods: Seventy-three rodents were collected from three regions (Gonbad, Gomishan and Bandar Turkmen) using live traps. In laboratory, morphometric characteristics were measured and for diagnosis of Leishmaniasis CL, the scratches obtained from their ears were examined by microscopic methods using Giemsa.
Results: The most frequent rodents were Meriones libycu (10.95%), Rattus norvegicus (21.91%), and Mus musculus (67.12%). Eleven (15.06%) of them were infected by cutaneous Leishmaniasis (CL).
Conclusion: Because of infection rate, there is a high transmission risk of CL in the studied region.
Keywords: Rodentia; Leishmaniasis; Turkmen Sahra; Meriones; Mus Musculus; Rattus Norvegicus
Fahime Mohammad Abadi , Arezoo Mirfazeli , Hossein Zaeri , Mojgan Nejabat, Mahsa Taherizadeh, Mohammad Ariaie , Azadeh Aliarab, Hamidreza Joshaghani,
Volume 10, Issue 2 (Mar,Apr2016 2016)
Abstract
ABSTRACT
Background and Objective: Measurement of amino acids is an important tool for metabolic studies and evaluation of patients’ clinical condition. The aim of this study was to analyze the plasma amino acids using reverse phase high performance liquid chromatography techniques (RP-HPLC) with pre-column derivatization by o-phthalaldehyde (OPA) in combination with 3- mercaptopropionic acid (3-MPA).
Methods: Overall, 107 neonates and babies suspected of having metabolic disorder were enrolled in this study. The level of amino acids in plasma samples was analyzed within 65 minutes by HPLC with pre-column derivatization by OPA/3-MPA. This was a gradient RP-HPLC method that was performed using two solvents with a ratio of methanol and sodium acetate. L-norvaline internal standard was used as the reference peak for amino acids. Standard mixture of amino acids was used to determine the concentrations of amino acids.
Results: According to the values of coefficient of variation obtained for each amino acid, the results indicated a good chromatographic separation of amino acids by this method. The use of OPA/3-MPA derivative reagent increased the efficiency and resolution of amino acids chromatographic separation.
Conclusion: Due to simple preparation and accurate assessment, determination of plasma amino acids using OPA/3-MPA derivatives and RP-HPLC is a suitable method in many clinical samples.
Saeideh Sadat Shobeiri , Saeid Abediankenari (phd), Mohtaram Nasrollahi , Mohammad Khademlou, Maryam Sarabijamab ,
Volume 10, Issue 3 (May-Jun 2016 2016)
Abstract
Background and objective: Implementation of standard methods for accurate detection of bacteria, correct antibiotic susceptibility testing and effective treatment of bacterial infections play important roles in development of public health and prevention of drug resistance. This study aimed to detect bacteria using standard methods and compare the results with the results obtained in teaching hospitals’ laboratories.
Methods: Positive culture plates containing bacteria isolated from patients in hospital laboratories in city of Sari were transferred to microbiology laboratory of Faculty of Medicine at Mazandaran University of Medical Sciences, after determining the genus and species of bacteria and antibiotic susceptibility testing of the isolates. The samples were re-examined based on standard protocols, and antibiotic susceptibility testing was done using the Kirby-Bauer method.
Results: Of 101 patients, 20% of bacteria and 22.5% of antibiotic sensitivity results reported by the hospital laboratories were incorrect. There were significant differences between the two study groups in terms of bacterial species detection and sensitivity to some drugs (P<0.05).
Conclusion: In the present study, lack of implementation of internal quality control programs in some hospital laboratories and lack of proper monitoring by regulatory authorities in different departments of the hospital have caused 20% false-detection results in hospital reports. Inconsistency in results of laboratories, false antibiograms and subsequent false laboratory reports cause drug resistance in some patients. This indicates the necessity of continuous training in the field of Microbiology and implementation of standard protocols and methods for detection of bacterial species and antibiotic susceptibility testing.
Mohammad Mohammad Mostakhdem Hashemi , Afsaneh Tabandeh , Hamidreza Tajari , Nasser Behnampour, Azadeh Aliarab, Hamid Reza Joshaghani,
Volume 10, Issue 4 (Jul-Aug 2016 2016)
Abstract
ABSTRACT
Background and Objectives: sperm motility mainly depends on aerobic glycolysis, and lactate dehydrogenase (LDH) is a key enzyme in the last step of this process. On the other hand, fructose is considered as the main energy source for sperm motility. Therefore, this study aimed to evaluate the LDH activity and fructose levels and their correlation with sperm motion parameters in normospermic and asthenozospermic males.
Methods: In this case-control study, 96 normospermic and 96 asthenozospermic males were enrolled. The semen samples were analyzed by computer assisted semen analysis to identify sperm motion parameters. Seminal plasma fructose levels were measured using Seliwanoff's test. LDH activity in the samples was evaluated using commercially available kits. The obtained data were analyzed by SPSS software (version 16).
Results: The levels of LDH activity and fructose concentration were not different between the two groups. There was no correlation found between LDH activity and fructose concentration or sperm motility parameters. However, LDH was significantly correlated with sperm concentration in both groups.
Conclusion: Although LDH activity and fructose levels seem to be influenced by sperm motility, other factors such as sperm concentration and total sperm count can also affect their seminal plasma levels. Thus, when the sperm concentrations are equal in study groups, the level of these factors are expected to be equal.
Keywords: Lactate Dehydrogenase, Fructose, Sperm Motility, CASA.
Abbass Ghanbari-Niaki , Fatemeh Islami, Ramezanali Arabameri, Aliakbar Sharifiyan,
Volume 11, Issue 5 (Sep - Oct 2017)
Abstract
ABSTRACT
Background and Objectives: The aim of the present study was to investigate the effect of six weeks of volleyball training on lipid and lipoprotein profiles of elite high school male volleyball players in the Golestan Province (Iran) during preparation season for an international championship in France.
Methods: Training group included 12 elite volleyball players in students’ premier league and control group included 12 healthy non-athlete male students. The training group practiced at 60-85% of maximum heart rate for six weeks, 90 minutes per session, six sessions per week and three sessions a day (first session: technical practice, second session: tactical practice and third session: technical/tactical practice). Blood samples were taken after 12 hours of fasting both before and after the training.
Results: Level of total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C) and LDL-C/HDL-C increased in the training group (P> 0.05). However, there was a significant difference between the two groups in TC and LDL-C levels (P<0.05). Level of triglyceride, VLDL, and TC/HDL-C reduced in the training group after six weeks of training (P> 0.05).
Conclusion: Our results show that the six-week volleyball training during the preparation season can cause abnormalities in plasma lipid profile.
Keywords: Lipid, Lipoprotein, Volleyball Player
Semira Kheiri , Azadeh Aliarab, Hamid Haghighatfard, Seyed Hossein Sadeghi ,
Volume 12, Issue 3 (May-Jun 2018)
Abstract
ABSTRACT
Background and objectives: 3' untranslated region (3'UTR) single nucleotide polymorphisms (SNPs) represent genetic variations that may potentially affect binding of miRNA to coding genes, potentially leading to complex disorders. We aimed to perform in silico analysis of the potential phenotypic effect of 3'UTR SNPs on human astrocyte elevated gene-1 (AEG-1), a newly identified candidate cancer gene.
Methods: We gathered a list of all 3'UTR SNPs located in the human AEG-1 gene from the SNP database. Analysis of the potential effects was done using MirSNP and MicroSNiper.
Results: Analysis by the MirSNP estimated that rs187728237 might increase the affinity of two miRNAs and decrease the affinity of 10 other miRNAs to the AEG-1 transcript. Moreover, MicroSNiPer showed that rs80320514 might affect 24 putative miRNA binding sites in the 3'UTR of AEG-1.
Conclusion: Based on our findings, it can be concluded that the 3'UTR SNPs located in the human AEG-1 gene may be within the miRNA targets of the transcript, therefore affecting the stability of putative miRNA-target interactions.
Keywords: AEG-1, miRNA, SNPs, 3' Untranslated Region.
Ameneh Arab, Alireza Mohebbi, Hamid Afshar, Abdolvahab Moradi,
Volume 12, Issue 5 (Sep-Oct 2018)
Abstract
ABSTRACT
Background and Objectives: Psychiatric disorders such as schizophrenia and bipolar disorder pose a high burden among the general population. Etiological factor(s) of such disorders remain unknown. Borna disease virus (BDV) is a neurotropic virus that has been suggested as an etiological agent for psychiatric disorders. Therefore, we aimed to investigate the prevalence of BDV among patients with schizophrenia and bipolar disorder.
Methods: Peripheral blood mononuclear cells (PBMCs) of schizophrenic (n=75) and bipolar (n=55) patients and healthy blood donors (n=125) were extracted form whole blood samples. RNA was extracted from PBMCs and the presence of BDV P40 RNA was assessed by reverse transcription-polymerase chain reaction.
Results: The BDV genome was not detected in any of the subjects. Positive family history of disease was significantly more frequent among patients (P=0.0001). There was a significant association between contact with animals and psychiatric illnesses (P<0.05). Moreover, education level differed significantly between the two groups (P<0.05).
Conclusion: The results indicate no evidence of BDV genome among patients with psychiatric disorders. Serological examination for BDV antigens or antibodies could provide further information in this regard. In addition, contact with cats is significantly more prevalent among patients with mental illnesses, which might be due to infection with Toxoplasma gondii.
Keywords: Borna disease virus, Psychiatric disorder, Schizophrenia, Bipolar disorder, Risk factors.
Minoo Dadban Shahamat, Asra Askari, Ramezan Arab Koohsar ,
Volume 15, Issue 2 (Mar-Apr 2021)
Abstract
Background and objectives: Elevated blood lipids and physical inactivity are known risk factors of atherosclerosis. The objective of this study was to compare effects of four weeks of high-intensity intermittent training (HIIT) and continuous walking on atherogenic indices of obese middle-aged men.
Methods: Study population consisted of 36 male teachers aged 35-50 years, with mean body mass index (BMI) of 30.7 ± 3.5 kg/m2 who were working in the city of Galikesh, northeastern Iran. The subjects were enrolled via purposeful sampling and were randomly divided into two experimental groups and a control group. Before and after the intervention, anthropometric characteristics (height, weight and BMI) and blood pressure of each subject were measured. Fasting blood samples were taken from the left brachial vein 12 hours before the first exercise session and 12 hours after the last exercise session to determine lipid profile. Data were analyzed using SPSS 18 at significance level of 0.05.
Results: The four-week walking exercise significantly decreased serum levels of low-density lipoprotein-cholesterol (LDL-C) (P=0.001) and triglyceride (P=0.001). In addition, the HIIT program significantly increased high-density lipoprotein level (HDL-C) (P=0.004) and significantly reduced LDL-C (P=0.049), LDL/HDL (P=0.002), triglyceride (p=0.01), BMI (P=0.027) and blood pressure (P=0.002). In addition, the results of ANOVA and (Scheffe test) showed a significant increase in HDL-C (P=0.042) values and a significant decrease in VLDL-C (P=0.032), LDL/HDL (P=0.041), triglyceride (P=0.024), BMI (P=0.048) and blood pressure (P=0.016) of HIIT group compared to the control group.
Conclusion: Our findings indicated that HIIT has beneficial effects on some risk factors of atherosclerosis and cardiovascular disease.
Zahra Eslami, Yahya Mohammadnajad Panah Kandi, Alireza Norouzi, Abdorreza Eghbal Moghanlou, Mehdi Sheikh Arabi, Vahideh Kazeminejad, Seyedeh Somayeh Hosseini Alarzi, Aref Saeidi, Hamidreza Joshaghani,
Volume 16, Issue 3 (May-Jun 2022)
Abstract
Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease caused by the accumulation of large amounts of fat in the hepatocytes. Given that atorvastatin is effective for treatment of NAFLD, the present study investigated effects of high-fat/fructose diet (HFFD) with atorvastatin on liver enzymes and lipid profile in a NAFLD rat model.
Methods: Thirty-two male Wistar rats were divided into four groups: 1) normal control, 2) HFFD control, 3) HFFD + atorvastatin, and 4) normal + atorvastatin. The groups received HFFD for 15 weeks to induce hepatosteatosis. Atorvastatin was administrated at the dose of 10 mg/kg/day. Lipid profile and liver enzymes were measured after eight weeks of intervention.
Results: Triglyceride, cholesterol, gamma-glutamyl transferase, and aspartate transaminase were significantly reduced in the HFFD + atorvastatin group compared with the HFFD control group. In addition, cholesterol, high-density lipoprotein, alkaline phosphatase, and gamma-glutamyl transferase were significantly increased in the normal + atorvastatin group compared with the normal control group. Low-density lipoprotein increased significantly in the HFFD + atorvastatin group and the normal + atorvastatin group compared with other groups. There was a significant difference in the alanine transaminase levels between the groups taking atorvastatin. In fact, alanine transaminase level was lowest in the normal + atorvastatin group.
Conclusion: Atorvastatin improves the lipid profile and fatty liver and controls liver enzymes. Therefore, it can be used with caution to improve the lipid profile and reduce the complications of NAFLD.
Mohammad Sadegh Naghizadeh, Mohsen Naseri, Gholamreza Anani Sarab, Afshin Derakhshani, Mohammad Fereidouni,
Volume 17, Issue 6 (Nov-Dec 2023)
Abstract
Background: Atopic dermatitis (AD) is a common allergic disorder. Detection of responsible pathogenic allergens in AD patients by reliable methods has a fundamental role in the prevention, management, and treatment of AD. This study was conducted to determine the most common allergens by the skin prick test (SPT) and immunoblotting among AD patients referring to an allergy clinic in Birjand City, Iran.
Methods: The presence of AD was confirmed by an expert allergist. Serum levels of total and specific immunoglobulin E (sIgE) against 30 food and inhalant allergens were evaluated by a commercial immunoblotting kit (AlleisaScreen).
Results: The skin prick test was performed by a battery of 17 allergens. In total, 34 AD patients (mean age, 28.76 ± 17.36 years; range, 1-60 years; F/M ratio: 0.88) were enrolled in this study. The sensitization rates to at least 1 fungus, pollen, food, or indoor allergen by the immunoblotting method were 32.35%, 61.76%, 52.94%, and 47.05%, respectively. The most prevalent allergens were ragweed (52.94), Olive tree (41.16), Eucalyptus (35.29), date palm (35.29), and grass mix (32.28).
Conclusion: The study found that 85.29% of the studied population were sensitized to at least 1 allergen. Pollens and date palms were the most common allergens among AD patients, but the pattern of sensitization in SPT and immunoblotting was not exactly similar. Detection of allergens to which patients are sensitized and avoidance can help in the management of the disease and its symptoms.
