Search published articles


Showing 2 results for Platelets
Comparison of Diagnostic Procedures for Platelet Products Contaminated with Strains of Staphylococcus Epidermidis and Klebsiella
M Vakili (phd), N Jomeh Pour, E Zarifi , M Baghbanian , A Dehghan , M Sahimi , L Gudarzi ,
Volume 9, Issue 3 (9-2015)
Abstract

Abstract

Background and Objective: Given that microbial contamination is the third largest cause of mortality caused blood transfusion, the examination of contamination in platelet concentrates is essential in blood transfusion centers. The purpose of this study was to achieve a rapid test for bacterial contamination of platelets concentration.

Material and Methods: This laboratory study was conducted on 14 bags of platelet concentrates prepared from Yazd Blood Transfusion Center. Six platelet bags were infected by Staphylococcus epidermidis; six by Klebsiella with a concentration of 150, 15 and 1.5, and two bags were considered as control. In specific intervals, the bags were sampled aseptically and examined by the methods including culture, gram stain, Glucose and PH measurement.

Result: Due to the presence of dextrose, the initial glucose level of platelet bags was above 300 mg/dl. The mean of  Glucose in contaminated platelet bags was progressively  decreased in  3 days in that it reached  165 mg/dl in the third day ( p = 0.002) . The level of PH had a declining process in that it averagely decreased from PH 7.3 to PH 5.2 (P=0.017(. The results of culturing and smear of the bacteria were different according to the concentrations used in the study.

Conclusion: We can detect the contamination of platelet bags by measuring the level of glucose and PH level in the least amount of time.

Keywords: Blood Platelets; Klebsiella; Staphylococcus Epidermidis.


The importance of blood products reservation management in tertiary hospitals: A case study from a tertiary educational hospital in the North East of Iran
Parsa Sheybani, Ata Nazarzadeh , Mohammad Reza Keramati, Seyyede Fatemeh Shams ,
Volume 20, Issue 3 (7-2026)
Abstract
Background: Blood products are vital yet scarce medical resources. In teaching hospitals, inefficient transfusion practices often lead to unnecessary waste, compromising both patient safety and healthcare costs. This study investigated the patterns and underlying causes of unused blood products at Imam Reza Hospital, a major tertiary center in northeast Iran, with the aim of identifying modifiable factors contributing to this problem.
Methods: This retrospective cross-sectional study extracted data from the Laboratory Information System (LIS) and the hospital dashboard for the period from March 2022 to 2025. Blood component reservation and return data from five large clinical departments were examined.
Results: Although the total number of returned units declined over time, the return percentage increased in the final year, indicating persistent inefficiencies. By department, Neurology and Gynecology showed the highest return percentages, whereas the Hematology-Oncology ward, Intensive Care Unit (ICU), and Emergency Department reported the highest absolute numbers of returns. Platelets were the most frequently returned product, whereas fresh frozen plasma had the highest relative return rate. The most consistently reported reason for returns was “Physician Decision / Order Canceled,” while returns due to “Patient Death” also showed a gradual increase over the study period.
Conclusion: The key problem identified was that, despite gradual improvements, systemic challenges-especially poor documentation, the absence of digital monitoring tools, and knowledge gaps in transfusion handling-continue to undermine efficient blood product use. Implementing the proposed plan, including real-time dashboards, mandatory documentation, clinical staff education, and AI-based demand prediction tools, could address these inefficiencies, substantially reduce waste, and enhance transfusion practices.

Page 1 from 1