Showing 5 results for Male
Morteza Vahed Jabbari , Aliakbar Abolfathi,
Volume 12, Issue 1 (1-2018)
Abstract
ABSTRACT
Background and Objectives: Osteoarthritis (OS) is the most common type of arthritis and joint disease, especially in women. Proinflammatory cytokines, biochemical factors, specially matrix metalloproteinases, and reactive oxygen species play important roles in joint destruction in this disease. Therefore, the present study aimed to evaluate level of inflammatory factors and its relationship with clinical symptoms of OS in female patients.
Methods: The study was performed on female patients with knee OS, referring to healthcare centers of Tabriz University of Medical Sciences. After measuring the weight and height of patients, clinical symptoms such as severity of pain and physical performance were evaluated using the Knee Injury and Osteopaedic Outcome Score questionnaire. Serum levels of IL-1β, TNF-α, and hs-CRP in fasting blood samples were measured using ELISA kits and immunoturbidimetric assays.
Results: There was a significant association between level of IL-1β and score of pain. There was no significant relationship between the clinical symptoms and level of other inflammatory factors.
Conclusion: The results of the present study showed that the increase in inflammatory factors is correlated with severity of pain in OS patients.
Keywords: Osteoarthritis Knee, Female, Inflammatory Markers.
Farnaz Aminian, Seyyed Mahmood Hejazi, Sadegh Cheragh Birjandi,
Volume 15, Issue 3 (5-2021)
Abstract
Background and objectives: Blood flow restriction training (BFRT) has gained substantial interest due to the lower required intensity, which may be beneficial for individuals who are not able to lift heavy weights. Therefore, we aimed at evaluating effects of 12 weeks of resistance training with and without blood flow restriction on follistatin (FST) concentrations and physical performance in elderly females.
Methods: Thirty elderly female were randomly assigned into the following groups: resistance training with blood flow restriction (BFRT; n=10), resistance training without blood flow restriction (WBFRT; n=10) and control ( n=10). The resistance training was carried out three session a week for 12 weeks. Serum concentrations of FST, muscular endurance and dynamic balance were assessed at baseline and after the 12week intervention.
Results: Significant main effects of time were observed for FST (p =0.03, η2 = 0.15), muscular endurance (p = 0.00, η2 = 0.59) and dynamic balance (p=0.00, η2 = 0.57). FST [BFRT= 1.4 ng/ml (effect size Cohen’s {d} = -0.8) significantly increased only in BFRT group. However, muscular endurance [BFRT= 95 (d= -4.1) and WBFRT = 32 (d= -0.9)] significantly increased in both intervention groups (P<0.05). In addition, dynamic balance [BFRT= -0.5 seconds (d= 2.2)] significantly increased only in the BFRT group (P<0.05).
Conclusion: BFRT was able to increase FST concentrations. Due to its mechanistic role in muscle mass alterations, elderly females can incorporate our BFRT protocol to improve anabolic conditions for muscular adaptations.
Sajad Jafari, Mohammad Fathi, Masoud Rahmati,
Volume 17, Issue 3 (5-2023)
Abstract
Background and objectives: Endurance exercise causes fatigue due to mitochondrial dysfunction and oxidative stress. The present study was designed to investigate the effects of taurine supplementation on lipids peroxidation and antioxidant activity during endurance activities.
Methods: Twenty-four male volunteers aged 27 ± 1.8 years and weighting 74.9 ± 5.9 kg were randomly divided into three groups: taurine supplementation (n=8), placebo (n=8), and control (n=8). The subjects completed a 28-day endurance training protocol. Biochemical parameters such as superoxide dismutase (SOD), glutathione peroxidase (GPX) activities, as well as malondialdehyde (MDA) concentrations (8 hours before the first session and 8 hours after the last session) and maximum rate of oxygen consumption, were measured to evaluate the antioxidant, lipid peroxidation, and VO2 max status respectively. Finally, data were analyzed by SPSS software at a significance level of <0.05.
Results: Taurine supplementation significantly increased SOD (p=0.001) and GPX (p=0.001) but significantly decreased MDA (p=0.001). However, it had no significant effect on the VO2 max.
Conclusion: The results of the present study indicate that taurine has antioxidant effects against endurance exercise-induced oxidant stress and lipid peroxidation.
Shuchismita ., Iffat Jamal , Vijayanand Choudhary ,
Volume 18, Issue 1 (1-2024)
Abstract
Plasma cell leukemia (PCL) is a rare form of plasma cell dyscrasia with 2 variants: the primary form, which occurs de novo in patients with no previous history of multiple myeloma (MM), and the secondary form, which represents a leukemic transformation in patients with a previously recognized MM. Unlike myeloma, PCL typically follows an aggressive course, and the median age at presentation is usually above 50 years. In this report, we present a case of primary PCL that manifested at 19, an exceptionally rare occurrence.
Mojtaba Raeisi , Fatemeh Hooshmand , Marziyeh Gheraati, Masood Aman Mohammadi , Negin Mehdinejad ,
Volume 19, Issue 4 (7-2025)
Abstract
Background: Due to the growing problem of antibiotic-resistant bacteria and rising consumer preference for natural food preservatives, there is an increased interest in plant-based antimicrobial agents. While Salix aegyptiaca (S. aegyptiaca), also known as Musk Willow, is a promising source of bioactive compounds, its antibacterial properties have not been extensively studied. Therefore, this research investigates the chemical composition and antibacterial effectiveness of essential oils extracted from the leaves and male inflorescences of S. aegyptiaca against important foodborne pathogens like Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), Listeria monocytogenes (L. monocytogenes), and Salmonella enteritidis (S. enteritidis).
Methods: Essential oils were extracted from the leaves and male inflorescences of S. aegyptiaca through hydrodistillation. The chemical composition of these oils was then determined by gas chromatography-mass spectrometry (GC-MS) to identify their bioactive constituents. The antibacterial efficacy of the extracted oils was assessed using several methods, including the determination of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), as well as diffusion assays (Agar disk and agar well diffusion).
Results: GC-MS analysis revealed that the leaf oil was predominantly composed of 1,4-dimethoxybenzene, citronellol, and eugenol, whereas carvone was the main constituent of the male inflorescence oil. The leaf oil demonstrated superior antimicrobial activity, particularly against S. aureus, for which the MIC was determined to be 1250 µg/mL. Both oils indicated limited efficacy against Gram-negative bacteria. Of the strains tested, S. aureus proved to be the most susceptible, while E. coli exhibited the highest resistance.
Conclusion: The essential oils extracted from S. aegyptiaca, especially from its leaves, have shown significant antibacterial effects against common foodborne pathogens. This suggests they could be used as natural food preservatives, offering a viable alternative to synthetic additives. Additional research is necessary to investigate their use in food products and to establish their toxicological safety.
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