Abstract

     Background and Objective: Aluminum Phosphide (ALP) is a solid non-organic phosphide with dark gray or dark yellow crystals. It reacts with stomach acid after ingestion and causes phosphine gas to be released. It is thought that phosphine causes toxicity from enzymatic interference and may even lead to cell death. This study aimed to investigate the effects of poisoning with rice tablet on levels of platelets, hemoglobin, white blood cells.

     Methods: The clinical records of 67 cases of acute oral toxicity with aluminum phosphide admitted to Baharloo hospital and 28 forensic autopsy cases in Kahrizak forensic research center were studied. Recorded information included vital signs, demographic characteristics, numerous laboratory and clinical findings, complications and all pathologic findings.

      Results: All patients had received standard symptomatic and supportive treatments. Among the tested subjects, 30 of 67 patients (44.8%) were male. The mean hemoglobin level of recovered and deceased individuals was 12.26 and 11.72 g/dl, respectively. There was a significant relationship between patients’ WBC counts and mortality where the mean level of WBC in the deceased  was more than that of the recovered (P=0.001). Mean SBP in the deceased and the recovered individuals was 79.67 ± 12.89 and 102.46 ± 22.57 mmHg, respectively.

      Conclusion: Consumption of rice tablets results in blood pressure alteration, hemoglobin levels, platelets and leukocyte count. Tracking these alterations can reduce the side effects and mortality rate in the cases of rice tablet poisoning.

     Keywords: Aluminum Phosphide, White Blood Cells, Hemoglobins, Blood Pressure, Patients

Background and objectives: The aim of this study was to investigate the effect of eight weeks of aerobic exercise on serum iron, serum ferritin, platelet count, mean platelet volume, and some immunity indices in non-athlete females.

• In this study, 30 non-athlete females aged 30-45 years were randomly divided into an experimental and a control group. The experimental group was subjected to perform aerobic exercise at 60-70% of maximal heart rate for eight weeks, three sessions per week and one hour per session. Blood parameters were measured before the exercise program and after the completion of program by taking 2 ml blood samples from the venous vein of the participants in the sitting position. Finally, t-test was used to compare the pre-test and post-test means of each group and independent t-test was used to compare the two groups at significance of 0.05.
• : After eight weeks of aerobic exercise, there was a significant increase in mean platelet volume and a significant decrease in serum iron and ferritin levels in the experimental group (P <0.05). There was a slight decrease in the number of platelets, white blood cells, granulocytes, monocytes and lymphocytes (P<0.05).

            Conclusion: We recommend physical education instructors, athletes and non-athletes to consider iron supplementation during aerobic exercise, and modify appropriate training intensity based on the fitness and age of trainees to prevent risk of anemia.
            KEYWORDS: Aerobic exercise, platelet, iron, ferritin, white blood cell.